XWH - 08 - 1 - 0540 TITLE : Targeting Thromboxane A 2 Receptor for Antimetastasis Therapy of Breast Cancer

s published: Xuejing Zhang, Man-Tzu Wang, Yong Tang, Yakun Chen, and Daotai Nie. Thromboxane A2 receptor (TP) in tumor cell motility and metastasis. Proc. Amer. Assoc. Cancer Res. 48: #3098, 2009. Grants submitted: Xuejing Zhang (PI), Daotai Nie (mentor). Aspirin, Thromboxane, and Breast Cancer Metastasis. Department of Defense Breast Cancer Research Program Predoctoral Training Grants. Articles published: Tang Y, and D. Nie. Role of GTPases in tumor cell migration and metastasis. Cell Movement (F Columbus, ed.). Nova Science Publisher, Hauppauge, NY. 2009. Chen Y, Tang Y, Chen S, and Nie D. Regulation of breast cancer cell responses to chemotherapy by pregnane X receptor. Cancer Biology & Therapy 8: 1265 1272. 2009. Walia V, Ming D, Kumar S, Nie D, and Elble R. hCLCA2 is a p-53-inducible inhibitor of breast cancer cell proliferation. Cancer Research 69: 6624 – 6632, 2009. PMID: 19654313. Zhang X, Nie D, and Chakrabarty S. Growth factors in tumor microenvironment. Frontiers in Biosciences 15: 151 165, 2010.